CareLit · DOI-Nachweis · Pneumologie
Cellular mechanisms of interstitial lung disease in children caused by mutations of the ABCA3-transporter
DOI 10.1055/s-0029-1247959
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Nachweis in CareLit
Autor:innenN Weichert, E Kaltenborn, A Hector, M Woischnik, S Moslavac, M Griese
ZeitschriftPneumologie
Ausgabe01/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: ABCA3 protein is an ABC lipid transporter found in alveolar type-II cells (ATII), where it localizes to the outer membrane of lamellar bodies (LB) which store surfactant. Mutations in the ABCA3 gene are the most common known genetic cause of respiratory distress syndrome in newborns and of late onset interstitial lung disease (ILD) in children. Even though clinical experience suggests a link between th…
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Zitierempfehlung
N Weichert, E Kaltenborn, A Hector, M Woischnik, S Moslavac, M Griese (2010) Cellular mechanisms of interstitial lung disease in children caused by mutations of the ABCA3-transporter. Pneumologie (01). https://doi.org/10.1055/s-0029-1247959
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