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Melatonin-insulin interactions in type 2 diabetic rats as well as patients

E Peschke, T Frese, I Stumpf, H Sucha, I Bazwinsky-Wutschke, E Mühlbauer · Klinische Neurophysiologie · Ausgabe 03/2010

DOI 10.1055/s-0030-1250854

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Autor:innenE Peschke, T Frese, I Stumpf, H Sucha, I Bazwinsky-Wutschke, E Mühlbauer
ZeitschriftKlinische Neurophysiologie
Ausgabe03/2010
Jahrgang / SeitenNicht angegeben

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Introduction: There is a well-documented link between melatonin and insulin. Morphological, molecular and functional investigations have shown that the pineal hormone melatonin (MT) reduces insulin secretion in vitro as well as in control and type 2 diabetic rats. The effects were mediated by specific, high-affinity, pertussis-toxin-sensitive, G-protein-coupled MT1- as well as MT2-membrane receptors, which were dete…

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Zitierempfehlung

E Peschke, T Frese, I Stumpf, H Sucha, I Bazwinsky-Wutschke, E Mühlbauer (2010) Melatonin-insulin interactions in type 2 diabetic rats as well as patients. Klinische Neurophysiologie (03). https://doi.org/10.1055/s-0030-1250854

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