CareLit · DOI-Nachweis · Klinische Neurophysiologie
Pharmacological modification of ATP-dependent microglial activation in a disease model of ALS
DOI 10.1055/s-0030-1251013
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Zschüntzsch, S Hülsmann, C Schnell, P Dibaj, C Neusch
ZeitschriftKlinische Neurophysiologie
Ausgabe03/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Acute or chronic damage of neuronal tissue leads to microglial (MG) activation which is a multistep process involving morphological changes, release of pro-inflammatory substances, proliferation and migration to the affected sites of the brain. Purines as soluble factors are implicated as candidates for the chemotactic attraction of microglia by activating ionotropic P2X and metabotropic P2Y receptors (R). Earlier e…
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Zitierempfehlung
J Zschüntzsch, S Hülsmann, C Schnell, P Dibaj, C Neusch (2010) Pharmacological modification of ATP-dependent microglial activation in a disease model of ALS. Klinische Neurophysiologie (03). https://doi.org/10.1055/s-0030-1251013
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