CareLit · DOI-Nachweis · Pneumologie
Hypoxia triggers an antimicrobial pathway in human alveolar macrophages
DOI 10.1055/s-0030-1251099
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Autor:innenS Stenger, D Nickel, M Wagner, JH Ficker, C Schumann
ZeitschriftPneumologie
Ausgabe03/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Objective: A tuberculous granuloma is a specialized cellular microenvironment with low oxygen tension. Nevertheless immunological studies on the interaction of Mtb and host macrophages are almost exclusively performed under normoxic (20%) conditions. The aim of this study was to investigate whether hypoxia influences the immune response of human alveolar macrophages (AM). Methods: Human AM were purified from broncho…
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Zitierempfehlung
S Stenger, D Nickel, M Wagner, JH Ficker, C Schumann (2010) Hypoxia triggers an antimicrobial pathway in human alveolar macrophages. Pneumologie (03). https://doi.org/10.1055/s-0030-1251099
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