CareLit · DOI-Nachweis · Pneumologie
Apoptosis and disturbed cellular composition in experimental emphysema
DOI 10.1055/s-0030-1251213
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Nachweis in CareLit
Autor:innenL Farkas, D Farkas, J Gauldie, W Shi, M Kolb
ZeitschriftPneumologie
Ausgabe03/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Transforming Growth Factor β (TGF-β) has a fundemental role in lung tissue maintenance. Mice deficient in the signalling molecule Smad3 develop centrilobular emphysema postnatally following abnormal alveolarization. The current study characterizes cellular mechanisms that are involved in alveolar destruction in these mice. Smad3 KO and WT mice were examined at different time points (8 wks, 12 wks and 20 wks). Lungs…
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Zitierempfehlung
L Farkas, D Farkas, J Gauldie, W Shi, M Kolb (2010) Apoptosis and disturbed cellular composition in experimental emphysema. Pneumologie (03). https://doi.org/10.1055/s-0030-1251213
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