CareLit · DOI-Nachweis · Pneumologie
Type I IFNs mediate innate intracellular defense to Legionella pneumophila
DOI 10.1055/s-0030-1251248
Bibliografische Angaben
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Autor:innenJ Lippmann, H Müller, V van Laak, S Shin, G Taylor, N Suttorp, C Roy, B Opitz
ZeitschriftPneumologie
Ausgabe03/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Legionella pneumophila is an intracellular pathogen which can cause severe pneumonia called Legionnaires' disease. Host innate immune responses to L. pneumophila depend on (I) the Toll-like receptors, (II), the NAIP5/IPAF inflammasome and (III) IFNγ-mediated antibacterial mechanisms. In our study we investigate a further innate defense mechanism potentially directed against Legionella infection, which is governed by…
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Zitierempfehlung
J Lippmann, H Müller, V van Laak, S Shin, G Taylor, N Suttorp, C Roy, B Opitz (2010) Type I IFNs mediate innate intracellular defense to Legionella pneumophila. Pneumologie (03). https://doi.org/10.1055/s-0030-1251248
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