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Role of p38 MAPK in trauma-hemorrhage and subsequent pneumococcal pneumonia

N Ding, K Dahlke, AK Janze, O Sommerfeld, NC Riedemann, UA Maus · Pneumologie · Ausgabe 03/2010

DOI 10.1055/s-0030-1251386

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Autor:innenN Ding, K Dahlke, AK Janze, O Sommerfeld, NC Riedemann, UA Maus
ZeitschriftPneumologie
Ausgabe03/2010
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: Poly-traumatized patients surviving the initial insult are highly susceptible to secondary pneumonia, frequently progressing into sepsis and multi-organ failure. However, the underlying mechanism of post-traumatic immune suppression is poorly understood. Methods/Results: Here, we investigated the role of MAPK signalling for the development of impaired lung innate defense in a two-hit model of trauma/hemo…

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N Ding, K Dahlke, AK Janze, O Sommerfeld, NC Riedemann, UA Maus (2010) Role of p38 MAPK in trauma-hemorrhage and subsequent pneumococcal pneumonia. Pneumologie (03). https://doi.org/10.1055/s-0030-1251386

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