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Role of cathepsin G and neutrophil elastase in the lung host defense against mycobacterial infections

K Steinwede, K Walter, S Aly, J Bohling, R Maus, O Schreiber, M Srivastava, F Länger, T Welte, S Ehlers, UA Maus · Pneumologie · Ausgabe 03/2010

DOI 10.1055/s-0030-1251391

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Autor:innenK Steinwede, K Walter, S Aly, J Bohling, R Maus, O Schreiber, M Srivastava, F Länger, T Welte, S Ehlers, UA Maus
ZeitschriftPneumologie
Ausgabe03/2010
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: Tuberculosis remains to be a major health threat with ˜ 8–10 million new infections and 2–3 million deaths per year worldwide. The current study aimed at elucidating the role of neutral serine proteases cathepsin G and neutrophil elastase in the lung host defense against mycobacterial infections. Methods and Results: We found that cathepsin G deficient mice responded with a significantly decreased surviv…

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Zitierempfehlung

K Steinwede, K Walter, S Aly, J Bohling, R Maus, O Schreiber, M Srivastava, F Länger, T Welte, S Ehlers, UA Maus (2010) Role of cathepsin G and neutrophil elastase in the lung host defense against mycobacterial infections. Pneumologie (03). https://doi.org/10.1055/s-0030-1251391

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