CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Polymorphism within connective tissue growth factor (CTGF) gene strongly predicts the marker of the ß-cell mass in non diabetic subjects
DOI 10.1055/s-0030-1253807
Bibliografische Angaben
Nachweis in CareLit
Autor:innenO Pivovarova, E Fisher, MO Weickert, H Boeing, AFH Pfeiffer, N Rudovich
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Connective tissue growth factor (CTGF) is a key determinant of progressive pancreas fibrosis and is up-regulated in Type 2 diabetes mellitus (T2DM). Recent studies indicate that CTGF promotes fibrogenesis both by enhancing pancreatic stellate cells proliferation and by releasing proinflammatory cytokines. CTGF inactivation in mice compromises islet cell proliferation during embryogenesis. Methods: We investiga…
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Zitierempfehlung
O Pivovarova, E Fisher, MO Weickert, H Boeing, AFH Pfeiffer, N Rudovich (2010) Polymorphism within connective tissue growth factor (CTGF) gene strongly predicts the marker of the ß-cell mass in non diabetic subjects. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0030-1253807
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