CareLit · DOI-Nachweis · Klinische Pädiatrie
Alterations of TP53 are associated with poor outcome in relapsed childhood acute lymphoblastic leukemia
DOI 10.1055/s-0030-1254454
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Hof, C van Schewick, S Krentz, G Koerner, K Seeger, C Hagemeier, A von Stackelberg, G Henze, C Eckert, R Kirschner-Schwabe
ZeitschriftKlinische Pädiatrie
Ausgabe05/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Prognosis of children with relapsed ALL has improved by treatment protocols using clinical markers. Further improvement will rely on the identification of molecular markers. Inactivation of the TP53 gene in cancer is associated with poor outcome. However, its role in relapsed ALL is still controversial. To clarify the significance of TP53 inactivation, we analysed 159 patients with first relapse enrolled in the ALL-…
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Zitierempfehlung
J Hof, C van Schewick, S Krentz, G Koerner, K Seeger, C Hagemeier, A von Stackelberg, G Henze, C Eckert, R Kirschner-Schwabe (2010) Alterations of TP53 are associated with poor outcome in relapsed childhood acute lymphoblastic leukemia. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0030-1254454
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