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C20orf94 deletion is frequently associated with TEL/AML1 positive childhood ALL and mediated by illegitimate V(D)J recombination

B Meissner, C Eckert, T Bartram, P Breithaupt, R Kirschner-Schwabe, G Cario, A Schrauder, A Moericke, A von Stackelberg, M Schrappe, M Stanulla · Klinische Pädiatrie · Ausgabe 05/2010

DOI 10.1055/s-0030-1254456

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Autor:innenB Meissner, C Eckert, T Bartram, P Breithaupt, R Kirschner-Schwabe, G Cario, A Schrauder, A Moericke, A von Stackelberg, M Schrappe, M Stanulla
ZeitschriftKlinische Pädiatrie
Ausgabe05/2010
Jahrgang / SeitenNicht angegeben

Kernaussage aus der Literatur

Abstract-Vorschau

To gain insight into the spectrum of molecular aberrations associated with childhood leukemia we performed 100k Affymetrix SNP-array analysis in 20 ALL samples. The results were validated by high-resolution custom-made CGH array analysis. Recurrent lesions (prevalence >10%) not previously described in association with specific biological subgroups were further characterized by PCR in a large representative patient c…

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B Meissner, C Eckert, T Bartram, P Breithaupt, R Kirschner-Schwabe, G Cario, A Schrauder, A Moericke, A von Stackelberg, M Schrappe, M Stanulla (2010) C20orf94 deletion is frequently associated with TEL/AML1 positive childhood ALL and mediated by illegitimate V(D)J recombination. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0030-1254456

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