CareLit · DOI-Nachweis · Klinische Pädiatrie
Clinical relevance of glucocorticoid receptor gene deletions in relapses of TEL-AML1 positive pediatric acute lymphoblastic leukemias
DOI 10.1055/s-0030-1254457
Bibliografische Angaben
Nachweis in CareLit
Autor:innenF Meyr, T Heiden, A Giese, R Ullmann, G Henze, K Seeger
ZeitschriftKlinische Pädiatrie
Ausgabe05/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
TEL/AML1 (ETV6/RUNX1) positive B-cell precursor (BCP) acute lymphoblastic leukemias (ALL) are common among childhood ALL (20–25%) and are associated with good prognosis of initial and relapsed disease. The probability of event-free survival (pEFS) in TEL/AML1 positive relapsed patients was found to be 0.70±0.04 versus 0.39±0.03 in fusion gene negative patients after intensified therapy according to the ALL-REZ BFM p…
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Zitierempfehlung
F Meyr, T Heiden, A Giese, R Ullmann, G Henze, K Seeger (2010) Clinical relevance of glucocorticoid receptor gene deletions in relapses of TEL-AML1 positive pediatric acute lymphoblastic leukemias. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0030-1254457
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