CareLit · DOI-Nachweis · Klinische Pädiatrie
Dic(9;20)(p13;q11)-positive B-cell precursor acute lymphoblastic leukemia: A genetic and clinical entity?
DOI 10.1055/s-0030-1254458
Bibliografische Angaben
Nachweis in CareLit
Autor:innenK Nebral, M Koenig, D Krehan, A Teigler-Schlegel, J Harbott, F Niggli, OA Haas, R Panzer-Gruemayer, A Attarbaschi, S Strehl
ZeitschriftKlinische Pädiatrie
Ausgabe05/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Cytogenetically defined dic(9;20)-positive leukemia accounts for ˜2% of pediatric BCP-ALL and is considered as unique genetic and clinical entity. However, at the molecular level the breakpoints in both chromosomes are heterogeneous, and thus, the formation of a dic(9;20) does not result in the expression of a consistent fusion gene. Hence, a dic(9;20) is generally associated with loss of genetic material, primarily…
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Zitierempfehlung
K Nebral, M Koenig, D Krehan, A Teigler-Schlegel, J Harbott, F Niggli, OA Haas, R Panzer-Gruemayer, A Attarbaschi, S Strehl (2010) Dic(9;20)(p13;q11)-positive B-cell precursor acute lymphoblastic leukemia: A genetic and clinical entity?. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0030-1254458
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