CareLit · DOI-Nachweis · Klinische Pädiatrie
High fidelity of phenotype and genotype in serial NOD/SCID pediatric acute lymphoblastic leukemia
DOI 10.1055/s-0030-1254460
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Queudeville, SM Eckhoff, KM Debatin, LH Meyer
ZeitschriftKlinische Pädiatrie
Ausgabe05/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Primary ALL cells are very difficult to culture in vitro and currently available cell lines only poorly reflect the heterogeneous nature of the disease. Many groups therefore use murine xenotransplantation models for primary pediatric ALL. But, to date it remains unclear as to what extent the characteristics of the original patient leukemia are retained over consecutive xenograft passages or whether there is selecti…
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Zitierempfehlung
M Queudeville, SM Eckhoff, KM Debatin, LH Meyer (2010) High fidelity of phenotype and genotype in serial NOD/SCID pediatric acute lymphoblastic leukemia. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0030-1254460
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