CareLit · DOI-Nachweis · Klinische Pädiatrie
Special aspects of stem cell therapy in patients with MLD
DOI 10.1055/s-0030-1254464
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Boehringer, F Gieseke, M Doering, B Kustermann-Kuhn, M Vaegler, R Handgretinger, I Mueller
ZeitschriftKlinische Pädiatrie
Ausgabe05/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Metachromatic leukodystrophy (MLD) is caused by mutations in the arylsulfatase A (ASA) gene and leads to demyelination in the CNS. In MLD, transplantation of hematopoietic stem cells is thought to establish a continuous endogenous source of ASA, which can be taken up by somatic cells of the recipient to correct their own lysosomal metabolism. We analysed 8 patients with MLD after transplantation regarding (i) toxici…
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Zitierempfehlung
J Boehringer, F Gieseke, M Doering, B Kustermann-Kuhn, M Vaegler, R Handgretinger, I Mueller (2010) Special aspects of stem cell therapy in patients with MLD. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0030-1254464
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