CareLit · DOI-Nachweis · Klinische Pädiatrie
Amplicon, genomic background and genome instability in heterogeneous MYCN amplified neuroblastoma
DOI 10.1055/s-0030-1254468
Bibliografische Angaben
Nachweis in CareLit
Autor:innenD Bogen, IM Ambros, G Amann, E Spuller, J Erichsen, B Brunner, R Ladenstein, T Martinsson, PF Ambros
ZeitschriftKlinische Pädiatrie
Ausgabe05/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
In the last decade, around 24% of MYCN amplified (MNA) neuroblastomas (NB) at the CCRI contained a varying number of tumor cells/areas without MNA and were defined as heterogeneously MYCN amplified (hetMNA) according to INRG biology guidelines. For the investigation of the genomic background of hetMNA tumors, up to 4 pieces of the same tumor from 5 patients were analyzed by interphase FISH (I-FISH), MLPA and 250k SN…
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Zitierempfehlung
D Bogen, IM Ambros, G Amann, E Spuller, J Erichsen, B Brunner, R Ladenstein, T Martinsson, PF Ambros (2010) Amplicon, genomic background and genome instability in heterogeneous MYCN amplified neuroblastoma. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0030-1254468
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