CareLit · DOI-Nachweis · Klinische Pädiatrie
Plk1 is a novel target for high-risk neuroblastoma therapy
DOI 10.1055/s-0030-1254472
Bibliografische Angaben
Nachweis in CareLit
Autor:innenF Goeser, S Ackermann, J Schulte, V Ehemann, A Eggert, B Hero, F Berthold, M Fischer
ZeitschriftKlinische Pädiatrie
Ausgabe05/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: To determine Plk1 as a potential target for neuroblastoma therapy. Methods: PLK1 transcript levels of 476 neuroblastomas were correlated with prognostic markers and outcome. Seven neuroblastoma cell lines were treated with various concentrations of BI 2536 and changes in cell proliferation and cell cycle distribution were determined. Nude mice with IMR-32 neuroblastoma xenografts were treated with BI 2536. Res…
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Zitierempfehlung
F Goeser, S Ackermann, J Schulte, V Ehemann, A Eggert, B Hero, F Berthold, M Fischer (2010) Plk1 is a novel target for high-risk neuroblastoma therapy. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0030-1254472
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