CareLit · DOI-Nachweis · Klinische Pädiatrie
SGK1– a novel prognostic marker & potential drug target in medulloblastoma
DOI 10.1055/s-0030-1254479
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Pleier, D Sturm, M Remke, H Witt, V Goidts, G Reifenberger, J Felsberg, A Kulozik, A Korshunov, P Lichter, S Pfister
ZeitschriftKlinische Pädiatrie
Ausgabe05/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Medulloblastoma comprises the most common malignant brain tumour in children. We performed array-CGH (n=120), genome-wide mRNA expression profiling (n=60) and immunohistochemistry (n=210) and correlated the results to clinical data. The genomic locus of Serum- and glucocorticoid-inducible kinase (SGK1) at 6q23 was frequently targeted by DNA copy-number gain in high-risk medulloblastoma, and elevated SGK1 mRNA and pr…
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Zitierempfehlung
S Pleier, D Sturm, M Remke, H Witt, V Goidts, G Reifenberger, J Felsberg, A Kulozik, A Korshunov, P Lichter, S Pfister (2010) SGK1– a novel prognostic marker & potential drug target in medulloblastoma. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0030-1254479
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