CareLit · DOI-Nachweis · Klinische Pädiatrie
KDM1A/LSD1 has a functional role in migration of medulloblastoma cells and their neuronal precursors
DOI 10.1055/s-0030-1254481
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Nachweis in CareLit
Autor:innenC Weingarten, T Thor, M Baumann, LC Heukamp, R Büttner, A Schramm, A Eggert, JH Schulte, K Pajtler
ZeitschriftKlinische Pädiatrie
Ausgabe05/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
DNA methylation and histone acetylation are important epigenetic regulators of gene expression in cancer. Histone methylation has recently been proven to be a reversible process regulated by lysine (K)-specific demethylase 1A (KDM1A/LSD1). We previously reported that KDM1A expression in primary medulloblastomas is correlated with adverse patient outcome. Growth and migration of medulloblastoma cells was reduced afte…
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Zitierempfehlung
C Weingarten, T Thor, M Baumann, LC Heukamp, R Büttner, A Schramm, A Eggert, JH Schulte, K Pajtler (2010) KDM1A/LSD1 has a functional role in migration of medulloblastoma cells and their neuronal precursors. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0030-1254481
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