CareLit · DOI-Nachweis · Klinische Pädiatrie
Proteasome inhibitor bortezomib induces apoptosis in prednisone-resistant childhood acute lymphoblastic leukemia cells
DOI 10.1055/s-0030-1254483
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Junk, M Lauten, M Stanulla, G Cario, N Wittner, M Schrappe, B Schlegelberger, N von Neuhoff
ZeitschriftKlinische Pädiatrie
Ausgabe05/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The response to initial glucocorticoid (gc) therapy in childhood acute lymphoblastic leukemia (ALL) reliably predicts the response to multi-agent chemotherapy. We detected members of the ubiquitin proteasome system (UPS) to be altered in gc resistant leukemic cell lines, suggesting that the associated pathways might be involved in multi-agent chemotherapy resistance in childhood ALL. To investigate whether the prote…
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Zitierempfehlung
S Junk, M Lauten, M Stanulla, G Cario, N Wittner, M Schrappe, B Schlegelberger, N von Neuhoff (2010) Proteasome inhibitor bortezomib induces apoptosis in prednisone-resistant childhood acute lymphoblastic leukemia cells. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0030-1254483
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