CareLit · DOI-Nachweis · Klinische Pädiatrie
STEAP1-specific T cells for immunotherapy of Ewing sarcoma
DOI 10.1055/s-0030-1254500
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Kailayangiri, B Altvater, S Landmeier, S Pscherer, M Hotfilder, L Liebsch, C Faber, V Vieth, H Juergens, C Rossig
ZeitschriftKlinische Pädiatrie
Ausgabe05/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Primary metastatic Ewing sarcoma involving the bone and/or bone marrow has remained largely incurable. We propose to use cytotoxic T cells (CTLs) specific for STEAP-1, a surface protein aberrantly expressed in Ewing sarcoma, as therapeutic tools to eradicate minimal residual disease and prevent tumor dissemination and relapse. STEAP-1-specific CTLs were successfully expanded from purified CD8+ T cells from 6 HLA-A2-…
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Zitierempfehlung
S Kailayangiri, B Altvater, S Landmeier, S Pscherer, M Hotfilder, L Liebsch, C Faber, V Vieth, H Juergens, C Rossig (2010) STEAP1-specific T cells for immunotherapy of Ewing sarcoma. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0030-1254500
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