CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
ABCB1 genetics predicts tacrolimus response in patients with ulcerative colitis. Running head: Tacrolimus Pharmacogenetics in IBD
DOI 10.1055/s-0030-1254701
Bibliografische Angaben
Nachweis in CareLit
Autor:innenKR Herrlinger, H Koc, M Schwab, S Winter, A Teml, EF Stange, K Fellermann, E Schaeffeler
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Objectives: Tacrolimus (TAC) is effective in steroid refractory ulcerative colitis (UC) but non-response and unpredictable adverse events are major limitations in clinical practice. In transplantation medicine genetic variants related to TAC metabolism (e.g., cytochrome P450 3A) ad TAC transport (e.g. P-glycoprotein/ABCB1) have been repeatedly associated with interindividual variability in response to tacrolimus. We…
Zitieren
Zitierempfehlung
KR Herrlinger, H Koc, M Schwab, S Winter, A Teml, EF Stange, K Fellermann, E Schaeffeler (2010) ABCB1 genetics predicts tacrolimus response in patients with ulcerative colitis. Running head: Tacrolimus Pharmacogenetics in IBD. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-0030-1254701
Mit CareLit weiterarbeiten