CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
PAR4 plays an endogenous antinociceptive role in inflammatory but not in stress-induced colorectal hyperalgesia in mice
DOI 10.1055/s-0030-1254740
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Nachweis in CareLit
Autor:innenA Annaházi, M Dabek, K Gecse, A Rosztóczy, R Róka, F Izbéki, V Theodoru, T Wittmann, H Eutamene, L Bueno
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Activation of proteinase-activated receptor-4 (PAR4) from the colonic lumen by its agonist (PAR4-AP) or cathepsin-G (Cat-G) has antinociceptive effect to colorectal distension (CRD) in mice in basal conditions. Aims: To clarify if PAR4 activation has antihyperalgesic effect in 2 visceral hypersensitivity models, water avoidance stress (WAS) and TNBS colitis, and to test if endogenous PAR4 activation is present in th…
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Zitierempfehlung
A Annaházi, M Dabek, K Gecse, A Rosztóczy, R Róka, F Izbéki, V Theodoru, T Wittmann, H Eutamene, L Bueno (2010) PAR4 plays an endogenous antinociceptive role in inflammatory but not in stress-induced colorectal hyperalgesia in mice. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-0030-1254740
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