CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The non-conjugated chenodeoxycholate induces severe mitochondrial damage and inhibits bicarbonate transport in pancreatic duct cells
DOI 10.1055/s-0030-1254784
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Nachweis in CareLit
Autor:innenJ Maléth, Z Rakonczay, V Venglovecz, A Balázs, Z Rázga, L Tiszlavicz, P Hegyi
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2010
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background: We have recently shown that a high contentration (1 mM) of non-conjugated chenodeoxycholate (CDC) had strong inhibitory effects on the activities of acid/base transporters (Na+/H+ exchanger (NHE), Na+/HCO3- cotransporter (NBC), Cl-/HCO3- exchanger (CBE)) of pancreatic ductal epithelial cells (PDEC). Our aim was to characterize the intracellular mechanisms of the inhibitory effects of bile acids. Methods:…
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Zitierempfehlung
J Maléth, Z Rakonczay, V Venglovecz, A Balázs, Z Rázga, L Tiszlavicz, P Hegyi (2010) The non-conjugated chenodeoxycholate induces severe mitochondrial damage and inhibits bicarbonate transport in pancreatic duct cells. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-0030-1254784
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