CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Elevated cysteine-protease activity in fecal supernatants of constipation predominant IBS patients: a new factor disrupting colonic epithelial barrier
DOI 10.1055/s-0030-1254808
Bibliografische Angaben
Nachweis in CareLit
Autor:innenR Róka, A Annaházi, K Gecse, A Rosztóczy, F Izbéki, T Molnár, O Inczefi, L Ferrier, V Bezirard, H Eutamene, V Theodoru, L Bueno, T Wittmann
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Fecal serine-protease activity is elevated in diarrhea type irritable bowel syndrome (IBS-D), and this luminal factor enhances colonic permeability and colorectal sensitivity in mice when infused intracolonically (ic.). Rectal hypersensitivity has been described in all IBS subgroups, including constipation predominant IBS (IBS-C). Other proteases, such as cysteine-proteases (CP) are present in feces, and these prote…
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Zitierempfehlung
R Róka, A Annaházi, K Gecse, A Rosztóczy, F Izbéki, T Molnár, O Inczefi, L Ferrier, V Bezirard, H Eutamene, V Theodoru, L Bueno, T Wittmann (2010) Elevated cysteine-protease activity in fecal supernatants of constipation predominant IBS patients: a new factor disrupting colonic epithelial barrier. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-0030-1254808
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