CareLit · DOI-Nachweis · Klinische Pädiatrie
ABCA3+/- mice have significantly decreased amounts of phosphatidylcholine and phosphatidylglycerol in lung tissue
DOI 10.1055/s-0030-1261416
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Nachweis in CareLit
Autor:innenR Mittal, L Jin, M Hammel, G Liebisch, G Schmitz, A Holzinger
ZeitschriftKlinische Pädiatrie
Ausgabe06/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: ABCA3 (ATP-binding cassette A3 transporter) is found predominantly in the membrane of lamellar bodies in lung type II alveolar cells, where it mediates ATP-dependent import of surfactant phospholipids. Haplotype analysis of the ABCA3 gene has identified a polymorphism which is significantly associated with respiratory distress and bronchopulmonary dysplasia in premature infants. Heterozygosity of ABCA3…
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Zitierempfehlung
R Mittal, L Jin, M Hammel, G Liebisch, G Schmitz, A Holzinger (2010) ABCA3+/- mice have significantly decreased amounts of phosphatidylcholine and phosphatidylglycerol in lung tissue. Klinische Pädiatrie (06). https://doi.org/10.1055/s-0030-1261416
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