CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in Caucasians
DOI 10.1055/s-0030-1263388
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Nachweis in CareLit
Autor:innenF Stickel, S Buch, K Lau, HM zu Schwabedissen, T Berg, M Ridinger, S Wiegandt, M Rietschel, C Schafmayer, F Braun, H Hinrichsen, R Günther, A Arlt, M Seeger, S Müller, HK Seitz, M Soyka, M Lerch, F Lammert, C Sarrazin, S Zeuzem, R Kubitz, D Häussinger, C Hellerbrand, J Schölmerich, D Bröring, S Sch…
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and Aims: A recent genome-wide study revealed an association between variation in the PNPLA3 gene and liver fat content. In addition, PNPLA3 single nucleotide polymorphism (SNP) rs738409 (M148I) was reported to be associated with advanced alcoholic liver disease in alcohol-dependent individuals of Mestizo descent. We therefore evaluated the impact of rs738409 on the manifestation of alcoholic liver diseas…
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Zitierempfehlung
F Stickel, S Buch, K Lau, HM zu Schwabedissen, T Berg, M Ridinger, S Wiegandt, M Rietschel, C Schafmayer, F Braun, H Hinrichsen, R Günther, A Arlt, M Seeger, S Müller, HK Seitz, M Soyka, M Lerch, F Lammert, C Sarrazin, S Zeuzem, R Kubitz, D Häussinger, C Hell… (2010) Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in Caucasians. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0030-1263388
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