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Activation of the Notch signaling pathway is involved in the formation of cholangiocellular carcinomas

S Zender, I Nickeleit, R Geffers, S Chauhan, S Kubicka, H Bektas, R Plentz, A Gossler, L Wilkens, MP Manns, NP Malek · Zeitschrift für Gastroenterologie · Ausgabe 08/2010

DOI 10.1055/s-0030-1263410

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Autor:innenS Zender, I Nickeleit, R Geffers, S Chauhan, S Kubicka, H Bektas, R Plentz, A Gossler, L Wilkens, MP Manns, NP Malek
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2010
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Throughout the last years the incidence of cholangiocellular carcinoma (CCC) in western european countries and the US is constantly rising. The pathogenesis of this devastating disease is however not well understood. Previously it was shown that the Notch signaling pathway is crucial for the development of the biliary system as loss of the Notch ligand Jagged results in hypoplasia of the biliary system (Alagille syn…

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Zitierempfehlung

S Zender, I Nickeleit, R Geffers, S Chauhan, S Kubicka, H Bektas, R Plentz, A Gossler, L Wilkens, MP Manns, NP Malek (2010) Activation of the Notch signaling pathway is involved in the formation of cholangiocellular carcinomas. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0030-1263410

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