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Activation of human immune cells by the oncolytic parvovirus H-1 combined with chemotherapeutic or targeted agents

M Moehler, M Sieben, S Roth, B Leuchs, C Dinsart, T Woelfel, J Rommelaere, P Galle · Zeitschrift für Gastroenterologie · Ausgabe 08/2010

DOI 10.1055/s-0030-1263593

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Autor:innenM Moehler, M Sieben, S Roth, B Leuchs, C Dinsart, T Woelfel, J Rommelaere, P Galle
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2010
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Oncolytic viruses, such as autonomous parvoviruses (PV) and their therapeutic vectors are known to stimulate potent antitumoral immune responses in vitro and in vivo. The parvovirus H-1 efficiently infects and lyses human tumor cells, including human melanoma, hepatoma, colon- and gastric cancer cells. The aim of our research project was now to further evaluate the biologic and immunologic effects of H-1PV-induced t…

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M Moehler, M Sieben, S Roth, B Leuchs, C Dinsart, T Woelfel, J Rommelaere, P Galle (2010) Activation of human immune cells by the oncolytic parvovirus H-1 combined with chemotherapeutic or targeted agents. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0030-1263593

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