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Prospective clinical validation of an assay for methylated SEPT9 DNA for use in detection of colorectal cancer in human plasma from average risk men and women over the age of 50

T Church, T Rösch, M Wandell, E Heiden, C Lofton-Day, M Burger, D Ransohoff · Zeitschrift für Gastroenterologie · Ausgabe 08/2010

DOI 10.1055/s-0030-1263603

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Autor:innenT Church, T Rösch, M Wandell, E Heiden, C Lofton-Day, M Burger, D Ransohoff
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2010
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Aims: A suitably sensitive and specific blood-based test for colorectal cancer (CRC) could appreciably increase the number of guideline eligible average risk individuals screened due to increased convenience and safety compared to other screening methods. Two previous case-control studies of clinically confirmed CRC demonstrated that detection of methylated SEPT9 DNA (mSEPT9) in plasma indicated the presence of CRC.…

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T Church, T Rösch, M Wandell, E Heiden, C Lofton-Day, M Burger, D Ransohoff (2010) Prospective clinical validation of an assay for methylated SEPT9 DNA for use in detection of colorectal cancer in human plasma from average risk men and women over the age of 50. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0030-1263603

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