CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
MMR status determines short-term apoptosis while growth speed determines necrosis and long-term survival of colon carcinoma cells after 5-FU treatment
DOI 10.1055/s-0030-1263611
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Autor:innenB Choudhary, ML Hanski, M Zeitz, C Hanski
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2010
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: Whether mutations in the hMLH1 gene, which is a component of the mismatch repair (MMR) system, increase or decrease the sensitivity of colon carcinomas to 5-fluorouracil (5-FU) is a matter of controversy. We investigated separately the effects of growth speed and of MMR status on apoptosis, necrosis and long-term survival of colon carcinoma cells after 5-FU treatment. Materials and methods: We used HCT…
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Zitierempfehlung
B Choudhary, ML Hanski, M Zeitz, C Hanski (2010) MMR status determines short-term apoptosis while growth speed determines necrosis and long-term survival of colon carcinoma cells after 5-FU treatment. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0030-1263611
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