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KRAS- and BRAF-Mutations and their clinical correlates in a prospective, multi-center, diagnostic clinical trial „molecular signatures in colorectal cancer“ (MSKK)

P Pechanska, R Mantke, R Pauli, K Ridwelski, K Hellwig, M Pross, C Radke, B Unger, H Lobeck, J Pertschy, H Kosmehl, T Manger, C Boltze, T Buthut, V Henn, B Hinzmann, I Klaman, HP Adams, D Nürnberg, A Rosenthal · Zeitschrift für Gastroenterologie · Ausgabe 08/2010

DOI 10.1055/s-0030-1263622

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Autor:innenP Pechanska, R Mantke, R Pauli, K Ridwelski, K Hellwig, M Pross, C Radke, B Unger, H Lobeck, J Pertschy, H Kosmehl, T Manger, C Boltze, T Buthut, V Henn, B Hinzmann, I Klaman, HP Adams, D Nürnberg, A Rosenthal
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2010
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Aims: KRAS mutation status is already used for tailoring therapy in colorectal cancer patients. Therefore, we investigated the relation of KRAS- and BRAF-status (mutated or wild type (WT)) with patient and tumor characteristics in the framework of a multi-center prospective study (MSKK) aiming at development of predictive and prognostic biomarkers. Methods: We have analyzed KRAS- and BRAF-mutation status in macro-di…

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P Pechanska, R Mantke, R Pauli, K Ridwelski, K Hellwig, M Pross, C Radke, B Unger, H Lobeck, J Pertschy, H Kosmehl, T Manger, C Boltze, T Buthut, V Henn, B Hinzmann, I Klaman, HP Adams, D Nürnberg, A Rosenthal (2010) KRAS- and BRAF-Mutations and their clinical correlates in a prospective, multi-center, diagnostic clinical trial „molecular signatures in colorectal cancer“ (MSKK). Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0030-1263622

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