CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome
DOI 10.1055/s-0030-1263662
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Nachweis in CareLit
Autor:innenC Bauer, P Düwell, C Mayer, HA Lehr, K Fitzgerald, J Tschopp, S Endres, E Latz, M Schnurr
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: The proinflammatory cytokines IL-1β and IL-18 are central players in the pathogenesis of inflammatory bowel disease (IBD). In response to a variety of microbial components and crystalline substances, both cytokines are processed via the caspase-1 activating multi-protein complex, the NLRP3 inflammasome. Here, we examined the role of the NLRP3 inflammasome in experimental colitis induced by dextran sulfate sodi…
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Zitierempfehlung
C Bauer, P Düwell, C Mayer, HA Lehr, K Fitzgerald, J Tschopp, S Endres, E Latz, M Schnurr (2010) Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0030-1263662
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