CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
EGF-IGF-1 signal cross-talk: ERK regulates Irs-1 transcription
DOI 10.1055/s-0030-1263797
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Autor:innenS Krishna-Subramanian, ML Hanski, M Zeitz, C Hanski
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: We observed that ursodeoxycholic acid (UDCA), whose potential as a chemopreventive agent is under investigation, inhibits proliferation of colonic epithelial cells. We investigated the effect of UDCA on EGF and IGF-1 signals, both of which regulate proliferation. Since a cross-talk between the IGF-1 and EGF pathways has been shown, we investigated also the effect of UDCA on the interaction of both path…
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Zitierempfehlung
S Krishna-Subramanian, ML Hanski, M Zeitz, C Hanski (2010) EGF-IGF-1 signal cross-talk: ERK regulates Irs-1 transcription. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0030-1263797
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