CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The common G/C variant in precursor miR-146a in the genetic predisposition to cholangiocarcinoma
DOI 10.1055/s-0030-1263805
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Autor:innenV Zimmer, F Mihalache, A Höblinger, F Grünhage, M Krawczyk, B Diaconu, BC Gärtner, T Sauerbruch, M Acalovschi, F Lammert
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and Aim: Micro RNAs (miRNAs) are small, non-coding RNA species considered to fine-tune basic cellular functions by modulation of target gene translation and/or mRNA stability. A common G/C polymorphism (rs2910164) in the precursor (pre-) miR-146a gene engaged in NF-κB signalling and apoptosis pathways has previously been reported to increase the genetic risk of hepatocellular carcinoma by increased G-alle…
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Zitierempfehlung
V Zimmer, F Mihalache, A Höblinger, F Grünhage, M Krawczyk, B Diaconu, BC Gärtner, T Sauerbruch, M Acalovschi, F Lammert (2010) The common G/C variant in precursor miR-146a in the genetic predisposition to cholangiocarcinoma. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0030-1263805
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