CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Selective inhibition of the chemokine receptor CCR1 by the non-peptide antagonist BX471 provides evidence for anti-fibrotic effects of CCR1 in liver
DOI 10.1055/s-0030-1263828
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Autor:innenS Weber, R Hall, I Adrian di Bondi, M Mahler, C Haskell, F Lammert, F Grünhage
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Induction: Progression and resolution of liver fibrosis are influenced by multiple chemokines. Recently, recruitment of peripheral blood monocytes via CCR2 stimulation has been shown to induce liver fibrosis in a toxic mouse model of liver fibrosis (Karlmark et al. Hepatology 2008;48:436A). In humans, monocyte recruitment is also influenced by CCR1 signalling (Heydtman & Adams. Hepatology 2009;49:676–88). Inhibition…
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Zitierempfehlung
S Weber, R Hall, I Adrian di Bondi, M Mahler, C Haskell, F Lammert, F Grünhage (2010) Selective inhibition of the chemokine receptor CCR1 by the non-peptide antagonist BX471 provides evidence for anti-fibrotic effects of CCR1 in liver. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0030-1263828
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