CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The pharmacological antagonist of the chemokine CCL5 (RANTES) Met-Rantes reduces experimental liver fibrosis in vivo
DOI 10.1055/s-0030-1263831
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Autor:innenML Berres, M Moreno Zaldivar, R Koenen, P Schmitz, C Weber, C Trautwein, HE Wasmuth
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2010
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Chronic liver inflammation leads to an activation of hepatic stellate cells with a consecutive excess of extracellular matrix proteins resulting in liver fibrosis. However, little is known about the factors mediating the interaction between inflammatory cells and hepatic stellate cells. We herein identify the inflammatory chemokine CCL5/RANTES which can be targeted by the competitive CCL5 antagonist Met-CCL5 a…
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Zitierempfehlung
ML Berres, M Moreno Zaldivar, R Koenen, P Schmitz, C Weber, C Trautwein, HE Wasmuth (2010) The pharmacological antagonist of the chemokine CCL5 (RANTES) Met-Rantes reduces experimental liver fibrosis in vivo. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0030-1263831
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