CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Impaired intestinal defensin production leads to bacterial translocation and subsequently aggravates hepatic inflammation and fibrogenesis in an experimental NASH model – a new second hit
DOI 10.1055/s-0030-1263834
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Nachweis in CareLit
Autor:innenE Gäbele, K Dostert, R Wiest, J Schölmerich, C Hellerbrand, F Obermeier
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2010
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Increased intestinal permeability and bacterial overgrowth and are pathophysiological factors of NASH in patients and in experimental models. Recently, we developed a new experimental setting combining a dietary NASH model with a model of chronic colitis, induced by application of dextran sulphate sodium (DSS), in order to study the liver-gut axis. Aim: The aim of the current study was to investigate the mecha…
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Zitierempfehlung
E Gäbele, K Dostert, R Wiest, J Schölmerich, C Hellerbrand, F Obermeier (2010) Impaired intestinal defensin production leads to bacterial translocation and subsequently aggravates hepatic inflammation and fibrogenesis in an experimental NASH model – a new second hit. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0030-1263834
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