CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Modelling hepatocellular carcinoma (HCC) initiation in mice with biliary fibrosis reveals strain- and gender-specific apoptosis rates
DOI 10.1055/s-0030-1263866
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Autor:innenSN Weber, F Lammert
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2010
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: In most patients, hepatocellular carcinoma (HCC) develops as a consequence of advanced fibrosis but the mechanisms are still incompletely understood. Recently it has been shown that initiation of HCC can be modelled by a single dose of the hepatocarcinogen diethylnitrosamine (DEN) in mice (Naugler et al. Science 2007). ABCB4-deficient mice develop biliary liver fibrosis and can be used as a spontaneous…
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Zitierempfehlung
SN Weber, F Lammert (2010) Modelling hepatocellular carcinoma (HCC) initiation in mice with biliary fibrosis reveals strain- and gender-specific apoptosis rates. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0030-1263866
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