CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Deficiency of complement factor c5 prevents the progression of biliary fibrosis in bile duct-ligated mice
DOI 10.1055/s-0030-1263910
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Autor:innenJ Schmitt, K Sabrane, M Roderfeld, P Zhang, Y Tian, J Mertens, P Frei, E Roeb, A Weber, B Müllhaupt, A Geier
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2010
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Fibrogenesis represents the universal response of the liver to chronic liver injury. Growing evidence indicates disease specific mechanisms of fibrosis initiation. Recently, C5 has been linked to fibrogenesis in a rodent model as well as in human chronic hepatitis C. C5 may also play a central role in fibrogenesis of chronic cholestatic disorders, since FXR has been characterized as an activator of the C3 gene…
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Zitierempfehlung
J Schmitt, K Sabrane, M Roderfeld, P Zhang, Y Tian, J Mertens, P Frei, E Roeb, A Weber, B Müllhaupt, A Geier (2010) Deficiency of complement factor c5 prevents the progression of biliary fibrosis in bile duct-ligated mice. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0030-1263910
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