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Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 (Lp-PLA2) mass and activity: Meta-analysis of genome-wide association studies from five community-based studies

J Baumert, J Bis, A Dehghan, M Barbalic, H Grallert, C Lu, R Schnabel, K Rice, J Witteman, R Tracy, W Koenig, E Benjamin, C Ballantyne · Das Gesundheitswesen · Ausgabe 09/2010

DOI 10.1055/s-0030-1266730

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Autor:innenJ Baumert, J Bis, A Dehghan, M Barbalic, H Grallert, C Lu, R Schnabel, K Rice, J Witteman, R Tracy, W Koenig, E Benjamin, C Ballantyne
ZeitschriftDas Gesundheitswesen
Ausgabe09/2010
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: Heritability of lipoprotein-associated phospholipase A2 (Lp-PLA2), an enzyme that generates pro-inflammatory and pro-atherogenic compounds in the arterial vascular wall and which may represent a therapeutic target in coronary heart disease (CHD), is incompletely understood. Methods: We sought to investigate genetic loci related to Lp-PLA2 mass or activity by conducting meta-analyses of genome-wide associ…

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Zitierempfehlung

J Baumert, J Bis, A Dehghan, M Barbalic, H Grallert, C Lu, R Schnabel, K Rice, J Witteman, R Tracy, W Koenig, E Benjamin, C Ballantyne (2010) Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 (Lp-PLA2) mass and activity: Meta-analysis of genome-wide association studies from five community-based studies. Das Gesundheitswesen (09). https://doi.org/10.1055/s-0030-1266730

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