CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Modulation of intracellular TGF-beta signalling by different PDGF isoforms and MEK1/2 in a murine hepatic stellate cell line
DOI 10.1055/s-0030-1269451
Bibliografische Angaben
Nachweis in CareLit
Autor:innenP Alexi, R Weiskirchen
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: TGF-β signalling plays an important, pro-fibrogenic role in liver fibrogenesis [1]. In addition it is known that the biological sequestering of platelet-derived growth factor (PDGF)-BB and PDGF-DD abrogates fibrogenic attributes in culture-activated hepatic stellate cells and in models of experimental hepatic fibrogenesis [2, 3]. Several previous reports further suggested that members of the PDGF family…
Zitieren
Zitierempfehlung
P Alexi, R Weiskirchen (2011) Modulation of intracellular TGF-beta signalling by different PDGF isoforms and MEK1/2 in a murine hepatic stellate cell line. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269451
Mit CareLit weiterarbeiten