CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Induction of HEME Oxygenase 1 reduces inflammation and fibrosis in a mouse model of chronic hepatitis
DOI 10.1055/s-0030-1269455
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Autor:innenR Barikbin, D Schwinge, C Schramm, G Tiegs, G Sass
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Heme oxygenase 1 (HO-1) is an essential enzyme in heme catabolism and has been shown to protect from acute inflammation induced liver damage. We now investigated effects of HO-1 induction in a mouse model of chronic hepatitis (Mdr2 knockout; Mdr2ko; FVB.129P2-Abcb4tm1Bor), characterized by fibrosis and progression to hepatocellular carcinoma (HCC). Methods: 5 or 12 weeks old Mdr2ko mice were treated with the H…
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Zitierempfehlung
R Barikbin, D Schwinge, C Schramm, G Tiegs, G Sass (2011) Induction of HEME Oxygenase 1 reduces inflammation and fibrosis in a mouse model of chronic hepatitis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269455
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