CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Recombinant expression, purification and functional impact of CTGF/CCN2 and NOV/CCN3 on liver fibrogenesis
DOI 10.1055/s-0030-1269456
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Autor:innenW Bohr, S Lux, E Borkham-Kamphorst, E Van de Leur, M Kupper, K Hoffmann, R Weiskirchen
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: The CCN family of proteins, especially its prominent member, the Connective tissue growth factor (CTGF/CCN2/) has been identified as a possible biomarker for the diagnosis of fibrotic diseases [1]. As a downstream mediator of TGF-β1, it regulates expression and deposition of extracellular matrix proteins and promotes cell proliferation [2]. Another member of this family, the Nephroblastoma-overexpressed…
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Zitierempfehlung
W Bohr, S Lux, E Borkham-Kamphorst, E Van de Leur, M Kupper, K Hoffmann, R Weiskirchen (2011) Recombinant expression, purification and functional impact of CTGF/CCN2 and NOV/CCN3 on liver fibrogenesis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269456
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