CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Expression and function of methylthioadenosine phosphorylase (MTAP) in chronic liver disease
DOI 10.1055/s-0030-1269460
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Autor:innenB Czech, A Stevens, G Kirovski, M Saugspier, C Dorn, D Valletta, A Bosserhoff, P Oefner, C Hellerbrand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Methylthioadenosine phosphorylase (MTAP) the rate-limiting enzyme in the methionine and adenine salvage pathways catalyzes the phosphorylation of 5′-deoxy-5′-(methylthio)adenosine (MTA) which is a by-product of polyamine synthesis. The aim of this study was to assess MTAP expression and function during the progression of chronic liver disease. Methods and Results: MTAP mRNA and protein expression were reduced in the…
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Zitierempfehlung
B Czech, A Stevens, G Kirovski, M Saugspier, C Dorn, D Valletta, A Bosserhoff, P Oefner, C Hellerbrand (2011) Expression and function of methylthioadenosine phosphorylase (MTAP) in chronic liver disease. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269460
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