CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
PD1 expression inhibits hepoatic inflammation and fibrosis in non-alcoholic steatohepatitis
DOI 10.1055/s-0030-1269465
Bibliografische Angaben
Nachweis in CareLit
Autor:innenC Dorn, C Blank, C Hellerbrand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
PD-L1 is a B7-family member that binds to programmed death-1 (PD-1). PD-1 is involved in the negative regulation of immune responses. Recently, we have shown that PD-L1 is expressed on hepatocytes, and that hepatocytes induce apoptosis in T-cells via PD-L1. The aim of this study was to analyzed the expression and function of PD-1 in non-alcoholic steatohepatitis (NASH) in which T-cells play an important pathophysiol…
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Zitierempfehlung
C Dorn, C Blank, C Hellerbrand (2011) PD1 expression inhibits hepoatic inflammation and fibrosis in non-alcoholic steatohepatitis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269465
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