CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
IL-13 induces connective tissue growth factor in rat hepatic stellate cells via TGF- independent Smad signaling
DOI 10.1055/s-0030-1269479
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Autor:innenY Liu, C Meyer, A Mueller, F Herweck, Q Li, R Muellenbach, PR Mertens, S Dooley, H Weng
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Connective tissue growth factor (CTGF) plays a central role in stimulating extracellular matrix deposition in the liver, and hence is considered as a critical mediator of TGF-β dependent fibrogenesis. Hepatic stellate cells (HSCs) are known as the major source of CTGF. However, previous studies revealed that IL-13, rather than TGF-beta, represents the main inducer of CTGF expression in HSCs. Methods: We evalua…
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Zitierempfehlung
Y Liu, C Meyer, A Mueller, F Herweck, Q Li, R Muellenbach, PR Mertens, S Dooley, H Weng (2011) IL-13 induces connective tissue growth factor in rat hepatic stellate cells via TGF- independent Smad signaling. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269479
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