CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
HGF/c-Met signaling in hepatocytes protects against progression of chronic liver fibrosis
DOI 10.1055/s-0030-1269483
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJU Marquardt, K Uchida, MC Gillen, D Seo, P Kaposi-Novak, EA Conner, VM Factor, SS Thorgeirsson
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
HGF/c-Met signaling plays a pivotal role in hepatocyte survival and tissue remodeling during liver regeneration. Treatment with HGF accelerates the resolution of fibrotic liver lesions in experimental animal models. To formally address the importance of c-Met signaling in hepatocytes in the context of chronic liver damage, we have used a model of chronic liver fibrosis in hepatocyte specific Metfl/fl;Alb-Cre±conditi…
Zitieren
Zitierempfehlung
JU Marquardt, K Uchida, MC Gillen, D Seo, P Kaposi-Novak, EA Conner, VM Factor, SS Thorgeirsson (2011) HGF/c-Met signaling in hepatocytes protects against progression of chronic liver fibrosis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269483
Mit CareLit weiterarbeiten