CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
TRAIL and TNFR1-dependent pathways and their role for progression of Nemo-dependent hepatitis
DOI 10.1055/s-0030-1269499
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Autor:innenA Singh, FJ Cubero, E Borkham-Kamphorst, M Al-Masaoudi, C Liedtke, T Luedde, R Weiskirchen, M Heikenwälder,, C Trautwein
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Hepatocyte-specific NEMO knockout mice (NemoΔhepa) show that the IκB kinase subunit NEMO/IKKγ is essential for activating the transcription factor NF-κB, which regulates cellular responses during inflammation, cell proliferation and apoptosis. Therefore we aimed to better characterise the protective pathways in death receptor-mediated hepatocyte apoptosis in NemoΔhepa animals. We generated NemoΔhepaTRAIL-/-, NemoΔhe…
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Zitierempfehlung
A Singh, FJ Cubero, E Borkham-Kamphorst, M Al-Masaoudi, C Liedtke, T Luedde, R Weiskirchen, M Heikenwälder,, C Trautwein (2011) TRAIL and TNFR1-dependent pathways and their role for progression of Nemo-dependent hepatitis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269499
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