CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Carbon monoxide protects primary mouse hepatocytes from induced apoptosis by activating the nitric oxide pathway
DOI 10.1055/s-0030-1269500
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Autor:innenJ Solomentsew, G Sass, G Tiegs
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and Aims: The anti-inflammatory, anti-viral and anti-apoptotic enzyme heme oxygenase-1 (HO-1) cleaves free heme by producing iron, biliverdin and carbon monoxide (CO). The anti-apoptotic effect of HO-1 has been attributed to its product CO, but the mechanism is not yet clear. Since HO-1 is over-expressed in many types of cancer, including hepatocellular carcinoma (HCC), we hypothesize that the HO-1 produc…
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Zitierempfehlung
J Solomentsew, G Sass, G Tiegs (2011) Carbon monoxide protects primary mouse hepatocytes from induced apoptosis by activating the nitric oxide pathway. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0030-1269500
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